TMEM147 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TMEM147	SYNE4
Description		transmembrane protein 147	spectrin repeat containing nuclear envelope family member 4
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein-containing Complex	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding Ribosome Binding	Protein Binding
	Biological Process		Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		55 interacting genes: ABHD16A ABI3 CD200 CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 DPM3 EBP EFNA4 ENPP4 F11R FFAR2 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PACC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC22A1 SLC22A2 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		10430	163183
HPRD ID		17633	08776
Ensembl ID		ENSG00000105677	ENSG00000181392
Uniprot IDs		Q9BVK8	Q8N205
PDB IDs		6W6L	6R16 6WMD
Enriched GO Terms of Interacting Partners?
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