TMEM147 and LHFPL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM147	LHFPL2
Description		transmembrane protein 147	LHFPL tetraspan subfamily member 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein-containing Complex	Cellular_component Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane
	Molecular Function	Protein Binding Ribosome Binding	Molecular_function Protein Binding
	Biological Process		Single Fertilization Biological_process Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)	Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		55 interacting genes: ABHD16A ABI3 CD200 CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 DPM3 EBP EFNA4 ENPP4 F11R FFAR2 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PACC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC22A1 SLC22A2 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12	11 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TBCA TMEM128 TMEM147
Entrez ID		10430	10184
HPRD ID		17633	17272
Ensembl ID		ENSG00000105677	ENSG00000145685
Uniprot IDs		Q9BVK8	A0A024RAM8 Q6ZUX7
PDB IDs		6W6L
Enriched GO Terms of Interacting Partners?
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