CITED2 and TBP

Number of citations of the paper that reports this interaction (PubMedID 10593900)
37

Data Source:
BioGRID (pull down)

		CITED2	TBP
Description		Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2	TATA-box binding protein
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-containing Complex	Chromatin Euchromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytoplasm Protein-containing Complex Transcription Preinitiation Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Histone Acetyltransferase Binding SMAD Binding LBD Domain Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase III General Transcription Initiation Factor Activity Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding TFIIB-class Transcription Factor Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Enzyme Binding General Transcription Initiation Factor Activity DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Response To Hypoxia Trophectodermal Cell Differentiation Neural Tube Closure Liver Development Embryonic Placenta Development Heart Looping Lens Morphogenesis In Camera-type Eye Hematopoietic Progenitor Cell Differentiation Outflow Tract Morphogenesis Regulation Of Animal Organ Formation Endocardial Cushion Development Transforming Growth Factor Beta Receptor Signaling Pathway Determination Of Left/right Symmetry Central Nervous System Development Peripheral Nervous System Development Heart Development Sex Determination Cell Aging Cell Population Proliferation Male Gonad Development Response To Mechanical Stimulus Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cranial Nerve Morphogenesis Positive Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Migration Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Granulocyte Differentiation Response To Fluid Shear Stress Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Adrenal Cortex Formation Skeletal Muscle Cell Differentiation Negative Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Decidualization Spleen Development Thymus Development Embryonic Camera-type Eye Morphogenesis Erythrocyte Development Negative Regulation Of Cardiac Muscle Cell Proliferation Embryonic Process Involved In Female Pregnancy Bone Morphogenesis Ventricular Septum Morphogenesis Embryonic Heart Tube Left/right Pattern Formation Left/right Pattern Formation Pulmonary Artery Morphogenesis Cardiac Neural Crest Cell Development Involved In Heart Development Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Left/right Axis Specification Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Positive Regulation Of Male Gonad Development	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription By RNA Polymerase III Spermatogenesis Positive Regulation Of Transcription, DNA-templated RNA Polymerase II Preinitiation Complex Assembly
Pathways		Regulation of gene expression by Hypoxia-inducible Factor TFAP2 (AP-2) family regulates transcription of other transcription factors Activation of the TFAP2 (AP-2) family of transcription factors FOXO-mediated transcription of cell death genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood trace element (Se levels) ( 23720494) Caudate volume in trauma-exposed individuals ( 29187748) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 30224653) Glycated hemoglobin levels ( 28898252) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899) IgA levels ( 28628107) Mean corpuscular hemoglobin ( 23263863 28453575 20139978 28017375 19862010) Mean corpuscular volume ( 23263863 32888494 28453575 20139978 28017375 19862010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Non-albumin protein levels ( 29403010) Obesity-related traits ( 23251661) Red blood cell traits ( 23222517) Systolic blood pressure ( 30224653) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Triglyceride levels ( 32203549) Triglycerides ( 25961943) Urate levels in lean individuals ( 25811787)	Type 1 diabetes ( 21980299)
Interacting Genes		11 interacting genes: CREBBP EP300 FBXL5 HIF1A LHX2 LHX3 MAPK1 TBP TFAP2A TFAP2B TFAP2C	124 interacting genes: ABT1 AHR AR ATF4 BCL3 BRD2 BRF1 BRF2 BTAF1 CAND2 CEP43 CITED2 COL26A1 CREG1 CREM CTBP1 CTCFL CUEDC2 CXXC1 DHX9 DR1 DRAP1 E2F1 EDF1 ELF3 ESR1 ETS1 FATE1 FOS FOXF2 GOLGA2 GTF2A1 GTF2A1L GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 GTF3C2 GTF3C3 GTF3C4 GTF3C5 H3-4 HAP1 HMBOX1 HMGB1 HNF4A HNRNPK HSF1 HTT HUWE1 IKZF1 JUN JUND JUP KDM5A KLF5 MBD2 MCM2 MDM2 MSX1 MYC NACA NCAPH NCOA1 NCOA3 NCOA6 NFE2L2 NFYB NFYC NR3C1 PAX3 PAX5 PAX6 PIAS1 PIAS3 POLR2A POLR3F POU2F1 POU2F2 POU3F2 PSMC2 PSME3 RB1 REL RELA REST RNF4 RUVBL1 RUVBL2 RXRA SERPINB5 SNAPC1 SNAPC2 SNAPC4 SP1 SPI1 SPIB SSX2IP SUB1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF1A TAF1B TAF1C TAF1L TAF5 TAF7L TCF12 TEAD1 TP53 TRAM2 TRIP4 UBE2I UBTF WDR62 YEATS2 YWHAE ZNF76
Entrez ID		10370	6908
HPRD ID		04245	02511
Ensembl ID		ENSG00000164442	ENSG00000112592
Uniprot IDs		A0A0A0MTM3 D9ZGF1 Q99967	P20226 Q32MN7
PDB IDs		1P4Q 1R8U	1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L
Enriched GO Terms of Interacting Partners?
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