HMG20B and WAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HMG20B	WAC
Description		high mobility group 20B	WW domain containing adaptor with coiled-coil
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Body	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	DNA Binding Protein Binding	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process	Chromatin Organization Cell Cycle Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Regulation Of Autophagy Positive Regulation Of Macroautophagy Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination Positive Regulation Of TORC1 Signaling
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)
Interacting Genes		29 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 TUBB4A USHBP1 VIM WAC	25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17
Entrez ID		10362	51322
HPRD ID		05703	18291
Ensembl ID		ENSG00000064961	ENSG00000095787
Uniprot IDs		Q9P0W2	Q9BTA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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