TRIM22 and LGALS8

Number of citations of the paper that reports this interaction (PubMedID 27693506)
111

Data Source:
BioGRID (pull down)

		TRIM22	LGALS8
Description		tripartite motif containing 22	galectin 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Body Nuclear Speck	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Integrin Binding Protein Binding Carbohydrate Binding
	Biological Process	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Immune Response Response To Virus Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Malaria ( 31844061)	Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		12 interacting genes: CASK CIC CREB1 LGALS3 LGALS8 MFHAS1 PLEKHF2 RERE TAF7 UBE2D1 USP7 ZZZ3	21 interacting genes: APEH BARD1 CALCOCO2 ERBB2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 TAX1BP1 TNFRSF18 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2
Entrez ID		10346	3964
HPRD ID		05951	09356
Ensembl ID		ENSG00000132274	ENSG00000116977
Uniprot IDs		B4DQS5 Q8IYM9	O00214
PDB IDs			2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z 6Z6Y
Enriched GO Terms of Interacting Partners?
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