LPAR6 and EMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LPAR6	EMP1
Description		lysophosphatidic acid receptor 6	epithelial membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lysophosphatidic Acid Receptor Activity	Protein Binding
	Biological Process	Blastocyst Hatching Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway	Cell Death Epidermis Development Bleb Assembly
Pathways		G alpha (q) signalling events P2Y receptors
Drugs		Promethazine
Diseases
GWAS		Lymphocyte counts ( 32888494)	Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 30598549 28869591) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin level ( 29403010)
Interacting Genes		5 interacting genes: EMP1 RPRM SEC22A SMIM3 TSC22D1	63 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 C1QBP CCR5 CD37 CD3G CD40 CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM262 TMEM31 TMEM9 TSPO2
Entrez ID		10161	2012
HPRD ID		16465	11892
Ensembl ID		ENSG00000139679	ENSG00000134531
Uniprot IDs		A0A024RDT2 B3KVQ5 P43657	A0A024RAT0 P54849
PDB IDs
Enriched GO Terms of Interacting Partners?
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