EBI3 and CANX

Number of citations of the paper that reports this interaction (PubMedID 8551575)
107

Data Source:
HPRD (in vivo)

		EBI3	CANX
Description		Epstein-Barr virus induced 3	calnexin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane External Side Of Plasma Membrane Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Rough Endoplasmic Reticulum Ribosome Membrane Axon Dendrite Cytoplasm Protein-containing Complex Melanosome Neuronal Cell Body Dendritic Spine Mitochondria-associated Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	Cytokine Receptor Activity Cytokine Activity Protein Binding Peptide Hormone Binding Cytokine Binding	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Apolipoprotein Binding Ionotropic Glutamate Receptor Binding Unfolded Protein Binding
	Biological Process	Humoral Immune Response Cytokine-mediated Signaling Pathway Positive Regulation Of Interferon-gamma Production Leptin-mediated Signaling Pathway T-helper 1 Type Immune Response Positive Regulation Of Alpha-beta T Cell Proliferation	Protein Folding Aging Protein Secretion Viral Protein Processing Ubiquitin-dependent ERAD Pathway Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis
Pathways		Interleukin-35 Signalling Interleukin-27 signaling	Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058) Triglyceride levels ( 32154731)	Daytime sleep phenotypes ( 27126917) Lymphocyte counts ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 32888494 27863252)
Interacting Genes		6 interacting genes: CANX GOSR1 IL12A IL27RA MDFI SMAD3	48 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 NUTF2 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR
Entrez ID		10148	821
HPRD ID		12051	00252
Ensembl ID		ENSG00000105246	ENSG00000127022
Uniprot IDs		Q14213	P27824
PDB IDs
Enriched GO Terms of Interacting Partners?
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