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CANX and F2RL1
Number of citations of the paper that reports this interaction (PubMedID
28298427
)
23
Data Source:
BioGRID
(two hybrid)
CANX
F2RL1
Description
calnexin
F2R like trypsin receptor 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Rough Endoplasmic Reticulum
Ribosome
Membrane
Axon
Dendrite Cytoplasm
Protein-containing Complex
Melanosome
Neuronal Cell Body
Dendritic Spine
Mitochondria-associated Endoplasmic Reticulum Membrane
Endoplasmic Reticulum Quality Control Compartment
Extracellular Exosome
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Glutamatergic Synapse
Integral Component Of Postsynaptic Membrane
Integral Component Of Presynaptic Active Zone Membrane
Early Endosome
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Pseudopodium
Molecular Function
RNA Binding
Calcium Ion Binding
Protein Binding
Carbohydrate Binding
Apolipoprotein Binding
Ionotropic Glutamate Receptor Binding
Unfolded Protein Binding
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
Signaling Receptor Binding
Protein Binding
Thrombin-activated Receptor Activity
G-protein Beta-subunit Binding
Signaling Receptor Activity
Biological Process
Protein Folding
Aging
Protein Secretion
Viral Protein Processing
Ubiquitin-dependent ERAD Pathway
Protein Folding In Endoplasmic Reticulum
Synaptic Vesicle Endocytosis
Clathrin-dependent Endocytosis
T Cell Activation Involved In Immune Response
Positive Regulation Of Leukocyte Chemotaxis
Positive Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Glomerular Filtration
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Coagulation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of Actin Filament Depolymerization
Positive Regulation Of Pseudopodium Assembly
Negative Regulation Of Chemokine Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Rho Protein Signal Transduction
Neutrophil Activation
Vasodilation
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of GTPase Activity
Innate Immune Response
Cell-cell Junction Maintenance
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of JNK Cascade
Negative Regulation Of JNK Cascade
Positive Regulation Of JNK Cascade
Leukocyte Migration
Positive Regulation Of Chemotaxis
Positive Regulation Of Positive Chemotaxis
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Defense Response To Virus
Positive Regulation Of Phagocytosis, Engulfment
Establishment Of Endothelial Barrier
Positive Regulation Of ERK1 And ERK2 Cascade
Thrombin-activated Receptor Signaling Pathway
Leukocyte Proliferation
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Mature Conventional Dendritic Cell Differentiation
Positive Regulation Of Renin Secretion Into Blood Stream
Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways
Assembly of Viral Components at the Budding Site
MHC class II antigen presentation
Interleukin-35 Signalling
Calnexin/calreticulin cycle
Interleukin-27 signaling
Maturation of spike protein
Maturation of spike protein
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Peptide ligand-binding receptors
G alpha (q) signalling events
Drugs
Antihemophilic factor, human recombinant
Tenecteplase
Lanoteplase
Calcium citrate
Calcium Phosphate
Lonoctocog alfa
Moroctocog alfa
Calcium phosphate dihydrate
Diseases
GWAS
Daytime sleep phenotypes (
27126917
)
Lymphocyte counts (
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
)
Resting heart rate (
24680774
)
White blood cell count (
32888494
27863252
)
Serum bilirubin levels x sex interaction in metabolic syndrome (
30621171
)
Interacting Genes
48 interacting genes:
ABCC2
APOB
BCAP31
CD1D
CD3D
CD82
CFTR
CSNK2A1
EBI3
EDEM1
F2RL1
F8
FAM107A
FSHR
GPR35
GRIA1
GRIN1
HLA-A
HTR3A
IFNGR1
ITGA6
ITGB1
LCT
LHCGR
LINC01554
LPA
LRP1
LTB4R2
MBTPS1
MDM2
MTNR1A
MTNR1B
NDRG1
NUTF2
PDIA3
PLP1
PMP22
PRKCSH
SERP1
SLC2A1
SLC4A1
SLC6A4
SMURF2
SUMO1
TF
TG
TRA
TSHR
84 interacting genes:
ABCC8
ABHD14A
ADCY2
ANKRA2
ARL6IP1
ATP2A2
ATP2B1
ATP2C1
BSG
CANX
CAPN1
CAPN2
CAPNS1
CBL
CD63
CD81
CLPTM1
CNN3
COPS5
CRLS1
CTNNA1
CTSG
CYFIP2
DNMT3L
ELANE
ERGIC3
F2
F2R
GJB6
GJC2
GPRASP1
HERPUD1
HLA-E
HMOX2
HSPA1B
ICAM2
JMY
KDELR1
KLC1
LMNA
MAP1B
MFSD10
MORN4
NAT14
NBPF15
NUMA1
OSTC
P4HTM
PCBD2
PHLDA1
PIGU
PLG
PPM1J
PRNP
PRRT2
PRTN3
PSMC3
PTDSS2
QSER1
R3HDM1
RAD17
RGR
RTN1
RTN4
SCN1B
SDHD
SLC12A5
SLC18B1
SLC1A4
SLC31A2
SLC32A1
SLC35A1
SLC39A13
SLC43A2
ST14
SYNGR2
TMBIM1
TMED1
TMEM161A
TMEM62
TMX2
WFS1
YIPF1
YIPF6
Entrez ID
821
2150
HPRD ID
00252
02960
Ensembl ID
ENSG00000127022
ENSG00000164251
Uniprot IDs
P27824
P55085
PDB IDs
5NDD
5NDZ
5NJ6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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