COX17 and UNC119

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COX17	UNC119
Description		cytochrome c oxidase copper chaperone COX17	unc-119 lipid binding chaperone
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Intermembrane Space	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone
	Molecular Function	Copper Ion Binding Protein Binding Copper Chaperone Activity Cuprous Ion Binding	Protein Binding Lipid Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Copper Ion Transport Brain Development Heart Development Positive Regulation Of Cell Population Proliferation Mitochondrial Cytochrome C Oxidase Assembly Positive Regulation Of Cytochrome-c Oxidase Activity	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Tau burden ( 33426524)
Interacting Genes		12 interacting genes: COPS6 EEF1A1 ERG28 HADHB KATNAL1 KRTAP10-8 LRIF1 PPBP RB1 RBM48 TP53 UNC119	103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24
Entrez ID		10063	9094
HPRD ID		05314	04927
Ensembl ID		ENSG00000138495	ENSG00000109103
Uniprot IDs		Q14061	K7EN86 Q13432
PDB IDs		2L0Y 2LGQ 2RN9 2RNB	3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A
Enriched GO Terms of Interacting Partners?
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