UNC119 and QTRT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UNC119	QTRT1
Description		unc-119 lipid binding chaperone	queuine tRNA-ribosyltransferase catalytic subunit 1
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GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone	Nucleus Mitochondrial Outer Membrane Protein-containing Complex
	Molecular Function	Protein Binding Lipid Binding	Queuine TRNA-ribosyltransferase Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	TRNA Modification TRNA-guanine Transglycosylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) FEV1 ( 30804560) Inflammatory skin disease ( 25574825) Lung function (FVC) ( 30804560) Psoriasis ( 25903422)
Interacting Genes		103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24	7 interacting genes: COPS6 NDUFA4L2 RHOU SETDB1 SH3GL3 UNC119 ZBTB16
Entrez ID		9094	81890
HPRD ID		04927	17943
Ensembl ID		ENSG00000109103	ENSG00000213339
Uniprot IDs		K7EN86 Q13432	Q71RF8 Q9BXR0
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A	6H42 6H45
Enriched GO Terms of Interacting Partners?
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