STRIT1 and HSD17B11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STRIT1	HSD17B11
Description		small transmembrane regulator of ion transport 1	hydroxysteroid 17-beta dehydrogenase 11
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Sarcoplasmic Reticulum Membrane	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding Enzyme Activator Activity	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Regulation Of Catalytic Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Estrogen Biosynthetic Process Androgen Catabolic Process
Pathways			Estrogen biosynthesis
Drugs			Aetiocholanolone
Diseases
GWAS			Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		45 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R F11R FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35C2 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6
Entrez ID		100507537	51170
HPRD ID			10881
Ensembl ID		ENSG00000240045	ENSG00000198189
Uniprot IDs			Q8NBQ5
PDB IDs			1YB1
Enriched GO Terms of Interacting Partners?
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