PDCD6 and MAPK1IP1L

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDCD6	MAPK1IP1L
Description		programmed cell death 6	mitogen-activated protein kinase 1 interacting protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Protein Kinase B Signaling Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs		Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS		Eye color ( 33692100) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Leukoderma in response to rhododendrol ( 32558222)
Interacting Genes		28 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CPNE1 CPNE2 CPNE4 CUL3 DIAPH3 FAS FASLG FNDC3A HEBP2 IGFALS MAP3K5 MAPK1IP1L MIA2 PDCD6IP PEF1 PRR19 SARAF SEC31A SH3KBP1 SHISA4 TERT TIMM22 VPS37C YWHAQ	26 interacting genes: ARHGEF16 C1orf94 CEP55 DAZAP2 EIF3E EWSR1 FUBP1 HGS HNRNPUL1 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-3 LENG8 MAGED1 MSX2 PDCD6 RAMAC RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG TIAL1 UBE2I VPS37C
Entrez ID		10016	93487
HPRD ID		03035	12647
Ensembl ID		ENSG00000249915	ENSG00000168175
Uniprot IDs		A0A024QZ42 A0A087WZ38 O75340 Q53FC3	Q8NDC0
PDB IDs		2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ
Enriched GO Terms of Interacting Partners?
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