PDCD6 and FNDC3A

Number of citations of the paper that reports this interaction (PubMedID 32878247)
3

Data Source:
BioGRID (far western blotting)

		PDCD6	FNDC3A
Description		programmed cell death 6	fibronectin type III domain containing 3A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome Endoplasmic Reticulum Exit Site	Golgi Membrane Acrosomal Vesicle Golgi Apparatus Cytosol Vesicle Membrane Membrane Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	RNA Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Protein Kinase B Signaling Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination	Spermatid Development Fertilization Sertoli Cell Development Cell-cell Adhesion
Pathways
Drugs		Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS		Eye color ( 33692100) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)	Apolipoprotein A1 levels ( 32203549) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol levels ( 32203549) Pelvic organ prolapse ( 26545240) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Trunk fat mass ( 28552196)
Interacting Genes		28 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CPNE1 CPNE2 CPNE4 CUL3 DIAPH3 FAS FASLG FNDC3A HEBP2 IGFALS MAP3K5 MAPK1IP1L MIA2 PDCD6IP PEF1 PRR19 SARAF SEC31A SH3KBP1 SHISA4 TERT TIMM22 VPS37C YWHAQ	3 interacting genes: APP NUDT15 PDCD6
Entrez ID		10016	22862
HPRD ID		03035	13548
Ensembl ID		ENSG00000249915	ENSG00000102531
Uniprot IDs		A0A024QZ42 A0A087WZ38 O75340 Q53FC3	A0A024RDT9 A0A024RDV5 Q9Y2H6
PDB IDs		2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ	1WK0 1X3D 1X4X 1X5X 2CRM 2CRZ
Enriched GO Terms of Interacting Partners?
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