PDCD6 and SEC31A

Number of citations of the paper that reports this interaction (PubMedID 32878247)
3

Data Source:
BioGRID (far western blotting, pull down)

		PDCD6	SEC31A
Description		programmed cell death 6	SEC31 homolog A, COPII coat complex component
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome Endoplasmic Reticulum Exit Site	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Vesicle Coat COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	Structural Molecule Activity Protein Binding Calcium-dependent Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Protein Kinase B Signaling Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Response To Calcium Ion COPII-coated Vesicle Cargo Loading
Pathways			COPII-mediated vesicle transport MHC class II antigen presentation XBP1(S) activates chaperone genes Signaling by ALK fusions and activated point mutants Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS		Eye color ( 33692100) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)	Adult asthma ( 27611488) Neutrophil percentage of white cells ( 27863252)
Interacting Genes		28 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CPNE1 CPNE2 CPNE4 CUL3 DIAPH3 FAS FASLG FNDC3A HEBP2 IGFALS MAP3K5 MAPK1IP1L MIA2 PDCD6IP PEF1 PRR19 SARAF SEC31A SH3KBP1 SHISA4 TERT TIMM22 VPS37C YWHAQ	15 interacting genes: APC ARIH1 FHL5 KLHL12 MYOM2 PDCD6 PEF1 PFDN1 PRNP REL SEC13 TNNT1 TSC1 TSC22D2 USP8
Entrez ID		10016	22872
HPRD ID		03035	15314
Ensembl ID		ENSG00000249915	ENSG00000138674
Uniprot IDs		A0A024QZ42 A0A087WZ38 O75340 Q53FC3	A0A024RDH6 A1LU61 O94979
PDB IDs		2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ	3WXA
Enriched GO Terms of Interacting Partners?
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