MELK and ZNF622

Data Source:
HPRD (in vivo, two hybrid)

		MELK	ZNF622
Description		maternal embryonic leucine zipper kinase	zinc finger protein 622
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell Cortex Membrane	Nucleoplasm Nucleolus Golgi Apparatus Cytosol Preribosome, Large Subunit Precursor
	Molecular Function	Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Lipid Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cell Population Proliferation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Peptidyl-tyrosine Phosphorylation Hemopoiesis Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Protein Autophosphorylation Neural Precursor Cell Proliferation	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Kinase Activity Ribosomal Large Subunit Biogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade
Pathways
Drugs		Fostamatinib
Diseases
GWAS			Attention function in attention deficit hyperactive disorder ( 26174813)
Interacting Genes		11 interacting genes: CDC25B CDC5L EIF2S1 EZH2 H1-5 LMNB1 MAPT MBP PPP1R8 SF3B1 ZNF622	7 interacting genes: APP BEND7 CDC42 HMGB2 MACROH2A1 MELK MYBL2
Entrez ID		9833	90441
HPRD ID		06119	12278
Ensembl ID		ENSG00000165304	ENSG00000173545
Uniprot IDs		B7Z1G6 Q14680	Q969S3
PDB IDs		4BKY 4BKZ 4BL1 4D2P 4D2T 4D2V 4D2W 4IXP 4UMP 4UMQ 4UMR 4UMT 4UMU 5IH8 5IH9 5IHA 5IHC 5K00 5M5A 5MAF 5MAG 5MAH 5MAI 5TVT 5TWL 5TWU 5TWY 5TWZ 5TX3 6GVX 6VXR	6LQM 6LSR
Enriched GO Terms of Interacting Partners?
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