CCP110 and CETN2

Data Source:
HPRD (two hybrid, in vivo)

		CCP110	CETN2
Description		centriolar coiled-coil protein 110	centrin 2
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Cilium Protein-containing Complex	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of Cilium Assembly Negative Regulation Of Centriole Elongation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Centriole Replication Spermatogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division Global Genome Nucleotide-excision Repair Ciliary Basal Body-plasma Membrane Docking
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 PCNT PNMA1 TFIP11 USP33	8 interacting genes: ARSA CCP110 PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC
Entrez ID		9738	1069
HPRD ID		10848	02051
Ensembl ID		ENSG00000103540	ENSG00000147400
Uniprot IDs		O43303	P41208
PDB IDs			1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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