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DZIP3 and BIRC3
Data Source:
BioGRID
(two hybrid)
DZIP3
BIRC3
Description
DAZ interacting zinc finger protein 3
baculoviral IAP repeat containing 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Phosphatase Binding
Polyubiquitin Modification-dependent Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Transferase Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Apoptotic Process
Cell Surface Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Protein Ubiquitination
Protein Deubiquitination
Positive Regulation Of Protein Ubiquitination
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Toll-like Receptor Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Regulation Of RIG-I Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Innate Immune Response
Regulation Of Inflammatory Response
Regulation Of Cell Cycle
Regulation Of Necroptotic Process
Negative Regulation Of Necroptotic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
NOD1/2 Signaling Pathway
TICAM1, RIP1-mediated IKK complex recruitment
RIPK1-mediated regulated necrosis
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
TNFR2 non-canonical NF-kB pathway
Regulation of necroptotic cell death
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Ub-specific processing proteases
IKK complex recruitment mediated by RIP1
Drugs
Diseases
GWAS
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
27863252
)
Prostate cancer (
23535732
)
Whole-brain volume (Alzheimer's disease interaction) (
21116278
)
Interacting Genes
52 interacting genes:
AKTIP
AP1M1
ARHGAP32
ATXN1
BAG4
BIRC2
BIRC3
CARM1
CEP63
DAZ1
FBXO17
GRIP1
GTF2H2C_2
HNRNPF
HNRNPH1
HNRNPUL1
HOTAIR
HOXC8
MIR20A
MIR29C
NCOR1
PCGF3
PITX1
RAD18
RBM4B
RNF38
RUNX1
TNS2
TOLLIP
TRIM21
TSG101
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2N
UBE2R2
UBE2U
UBE2V1
UBE2V2
UBE2W
UBE2Z
UBR3
ZCCHC10
ZNF24
ZNF765
41 interacting genes:
BCL10
BIRC5
CASP3
CASP7
CASP9
CD40
CYFIP2
DIABLO
DZIP3
GLMN
GSPT1
HAX1
HTRA2
IKBKE
IKBKG
MAP3K14
MBTPS1
PACS2
PELI1
RAF1
RCHY1
RIPK1
RIPK2
RIPK3
RIPK4
SNX7
SPHK1
SUMO1
TRAF1
TRAF2
TRAF3
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2N
UBE2Q2
UBE2V1
USP19
YOD1
Entrez ID
9666
330
HPRD ID
10562
03426
Ensembl ID
ENSG00000198919
ENSG00000023445
Uniprot IDs
Q86Y13
Q13489
PDB IDs
2UVL
3EB5
3EB6
3M0A
3M0D
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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