TCL1B and LSM7

Data Source:
BioGRID (two hybrid)

		TCL1B	LSM7
Description		TCL1 family AKT coactivator B	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity	MRNA Splicing, Via Spliceosome Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Parkinson's disease ( 28892059)
Interacting Genes		17 interacting genes: AKT1 AKT2 APP BAG4 EFCAB2 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330	25 interacting genes: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26
Entrez ID		9623	51690
HPRD ID		04795	06287
Ensembl ID		ENSG00000213231	ENSG00000130332
Uniprot IDs		A0A024R6P4 O95988	Q9UK45
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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