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MAP3K13 and PRDX3
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo, two hybrid)
MAP3K13
PRDX3
Description
mitogen-activated protein kinase kinase kinase 13
peroxiredoxin 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Membrane
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Early Endosome
Cytosol
Protein-containing Complex
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
JUN Kinase Kinase Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Enzyme Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
IkappaB Kinase Complex Binding
Protein Binding
Protein C-terminus Binding
Thioredoxin Peroxidase Activity
Alkyl Hydroperoxide Reductase Activity
Kinase Binding
Protein Kinase Binding
Identical Protein Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Biological Process
Activation Of MAPKK Activity
Protein Phosphorylation
JNK Cascade
Activation Of JNKK Activity
Activation Of JUN Kinase Activity
Positive Regulation Of Neuron Maturation
Peptidyl-serine Phosphorylation
Positive Regulation Of Axon Extension
Protein Autophosphorylation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Neuron Projection Arborization
Positive Regulation Of Branching Morphogenesis Of A Nerve
Maternal Placenta Development
Apoptotic Process
Response To Oxidative Stress
Mitochondrion Organization
Positive Regulation Of Cell Population Proliferation
Peptidyl-cysteine Oxidation
Myeloid Cell Differentiation
Response To Lipopolysaccharide
Negative Regulation Of Kinase Activity
Cellular Response To Oxidative Stress
Cellular Response To Reactive Oxygen Species
Response To Hydrogen Peroxide
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Redox Homeostasis
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Mitochondrial Membrane Potential
Cellular Oxidant Detoxification
Pathways
Detoxification of Reactive Oxygen Species
Drugs
Fostamatinib
Diseases
GWAS
Airflow obstruction (
22837378
)
Arterial stiffness index (
31235810
)
Major depressive disorder (
27519822
)
Alcoholic chronic pancreatitis (
28754779
)
Interacting Genes
8 interacting genes:
GLO1
HLA-DRB3
IKBKB
MAP2K7
MAPK8IP1
PRDX3
STAT3
TRIM25
15 interacting genes:
CDC42
CUL4B
FANCC
GORASP2
HNRNPD
MAGEA11
MAP3K13
NEK6
NR3C1
PRDX4
PTEN
RPS6KC1
SUMO4
TNFRSF1A
ZNF77
Entrez ID
9175
10935
HPRD ID
05372
05305
Ensembl ID
ENSG00000073803
ENSG00000165672
Uniprot IDs
O43283
A0A384MTR2
P30048
PDB IDs
5JCG
5UCX
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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