SESTD1 and STMN1

Data Source:
BioGRID (two hybrid)

		SESTD1	STMN1
Description		SEC14 and spectrin domain containing 1	stathmin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Calcium Channel Complex Intermediate Filament Cytoskeleton	Cytoplasm Cytosol Microtubule Membrane Neuron Projection Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylcholine Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding Tubulin Binding
	Biological Process	Negative Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel	Mitotic Cytokinesis Microtubule Depolymerization Mitotic Spindle Organization Signal Transduction Axonogenesis Brain Development Response To Virus Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Negative Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Negative Regulation Of Stress Fiber Assembly Establishment Of Skin Barrier Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways			Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Late-onset Alzheimer's disease ( 27770636) Objective response to lithium treatment ( 26503763) Optic disc size ( 31809533) Presence of antiphospholipid antibodies ( 23509613) Refractive error ( 32231278) Serum uric acid levels ( 29559957)
Interacting Genes		10 interacting genes: CBX8 DACT3 GPS2 HSF4 IQCB1 RABGEF1 STMN1 STMN2 TEAD4 ZNF830	17 interacting genes: CAMK2G CDK1 CDKN1B CHEK2 CSNK2A1 ERBB2 FANCC GLP1R HSPA5 HSPA8 MAPK3 PRKACA SEPTIN2 SESTD1 STAT3 UBQLN4 UHMK1
Entrez ID		91404	3925
HPRD ID		11549	01047
Ensembl ID		ENSG00000187231	ENSG00000117632
Uniprot IDs		B3KTX3 Q86VW0	A0A140VJW2 P16949
PDB IDs
Enriched GO Terms of Interacting Partners?
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