STMN1 and SESTD1

Data Source:
BioGRID (two hybrid)

		STMN1	SESTD1
Description		stathmin 1	SEC14 and spectrin domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Membrane Neuron Projection Extracellular Exosome	Calcium Channel Complex Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Tubulin Binding	Phosphatidylserine Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylcholine Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Mitotic Cytokinesis Microtubule Depolymerization Mitotic Spindle Organization Signal Transduction Axonogenesis Brain Development Response To Virus Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Negative Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Negative Regulation Of Stress Fiber Assembly Establishment Of Skin Barrier Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Negative Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS			Late-onset Alzheimer's disease ( 27770636) Objective response to lithium treatment ( 26503763) Optic disc size ( 31809533) Presence of antiphospholipid antibodies ( 23509613) Refractive error ( 32231278) Serum uric acid levels ( 29559957)
Interacting Genes		17 interacting genes: CAMK2G CDK1 CDKN1B CHEK2 CSNK2A1 ERBB2 FANCC GLP1R HSPA5 HSPA8 MAPK3 PRKACA SEPTIN2 SESTD1 STAT3 UBQLN4 UHMK1	10 interacting genes: CBX8 DACT3 GPS2 HSF4 IQCB1 RABGEF1 STMN1 STMN2 TEAD4 ZNF830
Entrez ID		3925	91404
HPRD ID		01047	11549
Ensembl ID		ENSG00000117632	ENSG00000187231
Uniprot IDs		A0A140VJW2 P16949	B3KTX3 Q86VW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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