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LMO4 and GADD45A
Data Source:
BioGRID
(two hybrid)
LMO4
GADD45A
Description
LIM domain only 4
growth arrest and DNA damage inducible alpha
Image
GO Annotations
Cellular Component
Transcription Regulator Complex
Cell Leading Edge
RNA Polymerase II Transcription Regulator Complex
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Molecular Function
Protein Binding
Transcription Factor Binding
Metal Ion Binding
Protein Binding
Kinase Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Protein N-terminus Binding
Promoter-specific Chromatin Binding
Biological Process
Neural Tube Closure
Ventricular Septum Development
Ventral Spinal Cord Interneuron Differentiation
Spinal Cord Motor Neuron Differentiation
Spinal Cord Association Neuron Differentiation
Regulation Of Cell Migration
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Kinase Activity
Regulation Of Cell Fate Specification
Positive Regulation Of Transcription By RNA Polymerase II
Thymus Development
Regulation Of Cell Activation
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Transcription By RNA Polymerase II
Activation Of MAPKKK Activity
DNA Repair
Apoptotic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Cell Cycle Arrest
Centrosome Cycle
Negative Regulation Of Angiogenesis
Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of JNK Cascade
Regulation Of Cell Cycle
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Mitotic Cell Cycle Arrest
Negative Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS
Angiotensin-converting enzyme inhibitor intolerance (
28030426
)
Breast cancer (
27354352
)
Eosinophil counts (
29403010
)
Gait rhythm (
26219847
)
Glaucoma (primary open-angle) (
29891935
)
Photic sneeze reflex (
27182965
)
Prostate-specific antigen levels (
28139693
)
Response to TNF antagonist treatment (
18615156
)
Resting heart rate (
27798624
)
White blood cell count (basophil) (
29403010
)
White blood cell types (
21738478
)
Bone mineral density (hip) (
30172743
)
Mean corpuscular volume (
29403010
)
Offspring birth weight (
31043758
)
Optic disc area (
28073927
)
Optic disc size (
31809533
)
Platelet distribution width (
32888494
)
Red blood cell count (
32888494
)
Interacting Genes
130 interacting genes:
AARD
ABI2
ADAMTSL4
AMOT
AMOTL2
ARNT2
BANP
BBS2
BCAS2
BIRC7
BRCA1
C12orf40
CALCOCO2
CCDC102B
CCDC120
CEP170P1
COG6
CRNN
CRYBB2
CSNK2B
CTBP2
CYSRT1
DDB1
DEAF1
DES
ECM1
ERCC6L
EXOSC8
FAM228A
FHL3
GABPB1
GADD45A
GOLGA2
GOLGA6L9
GRHL2
GSK3B
HELT
HGS
HSF2BP
ID3
IKZF1
IKZF3
ITSN1
KANK2
KATNBL1
KIAA1958
KIF3B
KPNA1
KRT15
KRT31
KRT33B
KRT34
KRT38
KRT39
KRT40
KRT74
KRT75
KRT76
KRTAP11-1
KRTAP3-1
KYNU
L3MBTL3
LASP1
LDB1
LDB2
LMO2
LZTS1
MCCD1
MERTK
METTL27
MID2
MTA1
MTUS2
MYOD1
MYOZ3
N4BP3
NFKBID
NFYC
NHLH1
NME4
NONO
NRF1
PDE4DIP
PELO
PER2
PITPNB
PLK1
PPARG
PPP1R32
QRICH1
RBAK
RBBP8
RBPMS
RCN1
RNF8
ROPN1
RPS6KA6
RSPH6A
SEC24D
SLC15A2
SMAD4
SMAD9
STAT5B
SUOX
TCF21
TCF4
TEX14
TFIP11
TINAGL1
TLE5
TNFSF11
TP53BP2
TRAF5
TRIM27
TRIM54
TSEN15
TTLL7
UBQLN2
VMAC
VPS52
WASHC1
ZBTB43
ZMYND12
ZNF135
ZNF202
ZNF213
ZNF397
ZNF410
ZNF467
ZNF675
69 interacting genes:
ADAP1
ASCC2
AURKA
BAG6
CBY2
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
CNOT9
DCTN2
DNAJC13
EEF1A1
EEF1G
ERG28
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
H1-1
H2AC16
H2BC21
H3-4
H4-16
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
LNX2
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PARVG
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS1
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
Entrez ID
8543
1647
HPRD ID
09122
00528
Ensembl ID
ENSG00000143013
ENSG00000116717
Uniprot IDs
P61968
A5JUZ3
P24522
PDB IDs
2L4Z
2KG4
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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