EEA1 and ZFYVE16

Data Source:
HPRD (in vitro)

		EEA1	ZFYVE16
Description		early endosome antigen 1	zinc finger FYVE-type containing 16
Image
GO Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Exosome	Early Endosome Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Metal Ion Binding
	Biological Process	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Viral RNA Genome Replication Early Endosome To Late Endosome Transport	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway
Pathways		Toll Like Receptor 9 (TLR9) Cascade	Signaling by BMP
Drugs		Inositol 1,3-Bisphosphate
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Sensorimotor dexterity ( 31596458) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Western dietary pattern ( 28644415)	Blond vs. brown/black hair color ( 30531825) Psoriasis ( 25854761)
Interacting Genes		13 interacting genes: IGF1R MAPK14 RAB22A RAB31 RAB5A RAB5B RAB5C RRAD STX12 STX6 TOM1 USO1 ZFYVE16	5 interacting genes: APP EEA1 PPP1CA RNF11 TOM1
Entrez ID		8411	9765
HPRD ID		05460	10319
Ensembl ID		ENSG00000102189	ENSG00000039319
Uniprot IDs		Q15075	Q7Z3T8
PDB IDs		1HYI 1HYJ 1JOC 3MJH	3T7L 5MK0
Enriched GO Terms of Interacting Partners?
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