ZFYVE16 and RNF11

Data Source:
HPRD (two hybrid)

		ZFYVE16	RNF11
Description		zinc finger FYVE-type containing 16	ring finger protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Metal Ion Binding	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways		Signaling by BMP
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Psoriasis ( 25854761)	Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)
Interacting Genes		5 interacting genes: APP EEA1 PPP1CA RNF11 TOM1	68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		9765	26994
HPRD ID		10319	09955
Ensembl ID		ENSG00000039319	ENSG00000123091
Uniprot IDs		Q7Z3T8	Q9Y3C5
PDB IDs		3T7L 5MK0
Enriched GO Terms of Interacting Partners?
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