STK40 and COP1

Data Source:
BioGRID (unspecified method)

		STK40	COP1
Description		serine/threonine kinase 40	COP1 E3 ubiquitin ligase
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GO Annotations	Cellular Component	Nucleoplasm Cytosol	Golgi Membrane Nucleoplasm Cytosol Nuclear Speck Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Respiratory System Process Glycogen Metabolic Process Protein Phosphorylation Regulation Of Gene Expression Multicellular Organism Growth Negative Regulation Of Apoptotic Process Regulation Of MAPK Cascade Lung Alveolus Development Lung Morphogenesis	Response To Ionizing Radiation Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways			Autodegradation of the E3 ubiquitin ligase COP1 Neddylation
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)
Interacting Genes		7 interacting genes: APP COP1 COPS6 LRRK2 NEDD4L POLA2 SLIRP	19 interacting genes: CCT4 CDKN1B DET1 ETS1 ETS2 JUN JUND MLF1 PTPN1 RB1CC1 SFN SIPA1 SOX2 STK40 TP53 TRIB1 UBE2D1 UBE2D2 YWHAZ
Entrez ID		83931	64326
HPRD ID		11359	07455
Ensembl ID		ENSG00000196182	ENSG00000143207
Uniprot IDs		Q8N2I9	Q8NHY2 X5D7N8 X5DNY7
PDB IDs		5L2Q	5HQG 5IGQ
Enriched GO Terms of Interacting Partners?
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