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USHBP1 and GTF2H1
Data Source:
BioGRID
(two hybrid)
USHBP1
GTF2H1
Description
USH1 protein network component harmonin binding protein 1
general transcription factor IIH subunit 1
Image
No pdb structure
GO Annotations
Cellular Component
Transcription Factor TFIIH Core Complex
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Molecular Function
Protein Binding
PDZ Domain Binding
Chromatin Binding
Protein Binding
Thyroid Hormone Receptor Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Duplex Unwinding
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Hormone-mediated Signaling Pathway
Nucleotide-excision Repair, DNA Incision
Positive Regulation Of Transcription, DNA-templated
Phosphorylation Of RNA Polymerase II C-terminal Domain
Global Genome Nucleotide-excision Repair
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS
Mitochondrial DNA copy number (
30704525
)
Amyloid A serum levels (
21124955
)
Blood protein levels (
28240269
)
Pancreatic cancer (
23180869
)
Serum metabolite levels (
23093944
)
Survival in pancreatic cancer (
28470677
)
Interacting Genes
234 interacting genes:
ABHD11
ABI2
ABLIM1
ACMSD
AKAP9
ANKRD33
ANKRD36BP1
ARFIP2
ARMC5
ARNT2
ASB15
ATP5PO
BCAS2
BCL10
BCL2L11
BET1
BEX2
BEX3
BFSP1
BFSP2
BICRAL
BLOC1S1
BLZF1
BORCS6
BRAT1
BRPF1
C1orf109
C1orf216
C21orf58
CBY2
CCDC103
CCDC116
CCDC120
CCDC121
CCDC146
CCDC148
CCDC187
CCDC196
CCDC197
CCDC22
CCDC24
CCDC28A
CCDC33
CCDC42
CCDC87
CCHCR1
CCNK
CDC37
CDC5L
CDKN1A
CENPP
CEP63
CEP68
CFAP206
CHCHD3
CNNM3
COPS4
COPS6
COPS8
CTNNA3
CTNNBIP1
CTTNBP2NL
CYTH4
DCTN2
DCTN3
DEPP1
DEUP1
DTNB
DYDC1
EIF4E2
ENKD1
ERCC1
EXOC7
EXOC8
FAM107A
FAM110A
FAM124B
FAM161B
FANCG
FATE1
FBF1
FCHSD2
FCRL5
FTL
GAS8
GATAD2B
GCC1
GEM
GFI1B
GIT2
GMCL2
GNG4
GOLGA6L9
GOLGA8EP
GOLGA8F
GPSM1
GPSM3
GTF2H1
HAUS1
HAUS8
HGS
HMG20A
HMG20B
HYI
IFT20
IL16
IMP3
ING3
INPP1
INTS4
ITGB3BP
KANK2
KANSL1
KIAA0753
KLC3
KLC4
KLHL38
KLHL42
KPNA2
KRT14
KRT15
KRT16
KRT19
KRT20
KRT26
KRT27
KRT28
KRT31
KRT37
KRT38
KRT40
KRT71
KRT75
KRT79
LENG1
LINC00526
MAGEB4
MCCD1
MCM7
MCRS1
MED11
MED28
MED4
MEI4
METTL15
MIIP
MKRN3
MNS1
MOS
MRPS23
MXI1
MYOG
MYOZ1
NCAPH2
NDC80
NDE1
NECAB2
NEFL
NOC4L
NUP62
ODAD3
OIP5
PARVG
PAX6
PBX4
PICK1
PKN1
PKNOX2
PMF1
POLM
POP5
PPP1R12C
PPP1R7
PPP2R5A
PPP2R5D
PRC1
PRKAA2
PRR5
QARS1
RASAL2
RCOR3
RECK
RIBC1
RIBC2
RINT1
RNF20
RTP5
SAPCD2
SAT1
SCNM1
SCT
SEC14L4
SEMA4C
SERTAD3
SH2D4A
SHC3
SMARCD1
SMARCE1
SOHLH1
SPG21
SRI
STX11
SYNJ2BP
TASOR2
TCEANC
TCHP
TEKT1
THADA
THOC1
TIMM13
TPRX1
TRIM54
TRIML2
TSG101
TTC23
TTC9C
TTLL10
TUBGCP4
TXLNA
TXLNB
UBE2W
UBXN11
USH1C
USP2
VPS28
ZBTB42
ZFHX3
ZFYVE26
ZNF417
ZNF483
ZNF655
ZNF688
ZNF765
ZNRF2P1
47 interacting genes:
ACTN1
AGTRAP
AR
ATF7IP
BRPF1
CCNH
CCSER2
CDK7
E2F1
EAF1
ERCC2
ERCC3
ERCC4
ERCC5
ESR1
FHL2
FUBP1
GTF2E1
GTF2E2
GTF2H2
GTF2H3
HNF4A
HNRNPU
HOXC11
JDP2
KIF13A
KPNA3
MCM2
MMS19
MNAT1
PIK3R1
PLCG1
POLR2A
POU2AF1
PSMC2
RAD23A
REEP5
RXRB
TNIP1
TP53
TRIOBP
TXNRD2
UBC
USHBP1
XPA
XPC
ZSCAN1
Entrez ID
83878
2965
HPRD ID
18276
01807
Ensembl ID
ENSG00000130307
ENSG00000110768
Uniprot IDs
A0A024R7H3
B4DUE8
G8JLM4
Q8N6Y0
Q8N8Y1
A0A384MTQ8
P32780
PDB IDs
1PFJ
2DII
2RNR
2RUK
2RVB
5GOW
5XV8
6NMI
6O9L
6O9M
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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