Wiki-Pi
About
Search
Browse
People
Updates
Search
GTF2H1 and GTF2H2
Data Source:
BioGRID
(pull down)
HPRD
(two hybrid, in vivo, in vitro)
GTF2H1
GTF2H2
Description
general transcription factor IIH subunit 1
general transcription factor IIH subunit 2
Image
GO Annotations
Cellular Component
Transcription Factor TFIIH Core Complex
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Core TFIIH Complex Portion Of Holo TFIIH Complex
Transcription Factor TFIIH Core Complex
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIH Holo Complex
Nuclear Speck
Molecular Function
Chromatin Binding
Protein Binding
Thyroid Hormone Receptor Binding
Protein Binding
Zinc Ion Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Protein N-terminus Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Duplex Unwinding
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Hormone-mediated Signaling Pathway
Nucleotide-excision Repair, DNA Incision
Positive Regulation Of Transcription, DNA-templated
Phosphorylation Of RNA Polymerase II C-terminal Domain
Global Genome Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Duplex Unwinding
G Protein-coupled Receptor Internalization
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Response To UV
Viral Process
Nucleotide-excision Repair, DNA Incision
Global Genome Nucleotide-excision Repair
Positive Regulation Of DNA Helicase Activity
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS
Amyloid A serum levels (
21124955
)
Blood protein levels (
28240269
)
Pancreatic cancer (
23180869
)
Serum metabolite levels (
23093944
)
Survival in pancreatic cancer (
28470677
)
Interacting Genes
47 interacting genes:
ACTN1
AGTRAP
AR
ATF7IP
BRPF1
CCNH
CCSER2
CDK7
E2F1
EAF1
ERCC2
ERCC3
ERCC4
ERCC5
ESR1
FHL2
FUBP1
GTF2E1
GTF2E2
GTF2H2
GTF2H3
HNF4A
HNRNPU
HOXC11
JDP2
KIF13A
KPNA3
MCM2
MMS19
MNAT1
PIK3R1
PLCG1
POLR2A
POU2AF1
PSMC2
RAD23A
REEP5
RXRB
TNIP1
TP53
TRIOBP
TXNRD2
UBC
USHBP1
XPA
XPC
ZSCAN1
14 interacting genes:
AR
CDK7
DNMT3L
ERCC2
ERCC3
ERCC8
ERRFI1
GTF2E1
GTF2H1
GTF2H3
GTF2H4
GTF2H5
MNAT1
SRA1
Entrez ID
2965
2966
HPRD ID
01807
03450
Ensembl ID
ENSG00000110768
ENSG00000145736
Uniprot IDs
A0A384MTQ8
P32780
Q13888
PDB IDs
1PFJ
2DII
2RNR
2RUK
2RVB
5GOW
5XV8
6NMI
6O9L
6O9M
1Z60
5IVW
5IY6
5IY7
5IY8
5IY9
5O85
5OF4
6NMI
6O9L
6O9M
6RO4
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?