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H3-4 and ATAD2
Data Source:
BioGRID
(pull down)
H3-4
ATAD2
Description
H3.4 histone
ATPase family AAA domain containing 2
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleosome
Nucleus
Nucleoplasm
Extracellular Exosome
Nucleus
Nucleoplasm
Extracellular Exosome
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Chromatin Binding
Protein Binding
ATP Binding
ATPase Activity
Histone Binding
Biological Process
Double-strand Break Repair Via Nonhomologous End Joining
Nucleosome Assembly
Telomere Capping
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Chromatin Silencing
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
Condensation of Prophase Chromosomes
DNA Damage/Telomere Stress Induced Senescence
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Meiotic recombination
Inhibition of DNA recombination at telomere
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS
Interacting Genes
198 interacting genes:
ADNP
AFF1
AHDC1
ANP32A
ASF1A
ASH2L
ATAD2
AURKA
AURKB
BIRC5
BMI1
BPTF
BRD7
C17orf49
CBX1
CBX2
CBX3
CBX4
CBX5
CBX7
CBX8
CDYL
CDYL2
CHAF1A
CHAF1B
CHAMP1
CHD1
CHD4
CHD6
CHUK
COPRS
CREBBP
CTBP1
CTBP2
DCAF1
DEK
DIDO1
DNMT1
DOT1L
DPF2
DPY30
DYRK2
EGFR
EHMT1
EHMT2
EMSY
EP300
ERAP1
EZH2
FOXA1
GADD45A
GATAD1
GLYR1
GTF3C4
HAT1
HDAC1
HDAC2
HDAC8
HIRIP3
HMGXB4
HNRNPA1
HNRNPA2B1
HNRNPAB
HNRNPK
HNRNPL
HNRNPR
HPF1
ING2
ING4
IRAK1
JADE2
JADE3
JAK1
JAK2
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM1B
KDM2A
KDM3B
KDM5A
KDM5D
KDM6A
KIF2A
KIF2C
KMT2A
KMT2C
KPNA1
LRIF1
LRWD1
MBD3
MCM2
MCM7
MDM2
MEN1
MGA
MIER1
MLLT1
MORF4L1
MSL3
MTA1
MTA2
MYB
NAP1L4
NASP
NBN
NCL
NCOA2
NCOA3
NOC2L
NONO
NPM1
NSD1
NSD2
ORC2
ORC3
ORC4
ORC5
PARP1
PARP2
PCGF6
PHC2
PHC3
PHF12
PHF7
PHF8
PHRF1
PIM1
POGZ
PPIB
PPM1G
PRDM2
PRKCA
PRMT5
PTBP1
PTMA
RAG1
RBBP4
RBBP5
RBBP7
RBP5
RCOR1
RING1
RIPPLY1
RNF2
RPS6KA3
RPS6KA5
RREB1
SAP30
SET
SETD2
SETD7
SETDB1
SFPQ
SGF29
SIN3A
SIN3B
SMN1
SMNDC1
SMYD3
SUPT20H
SUPT3H
SUV39H1
SUZ12
TADA1
TADA3
TAF1
TAF10
TAF11
TAF12
TAF13
TAF15
TAF1A
TAF2
TAF3
TAF4
TAF4B
TAF5
TAF5L
TAF6
TAF6L
TAF7
TAF8
TAF9
TAF9B
TBP
TCF19
TDRD3
TNPO1
TRPM7
UHRF1
WDR5
ZMYM4
ZMYND11
ZNF217
ZNF516
12 interacting genes:
BAG4
BCAR3
CASP8
E2F1
E2F2
E2F3
E2F4
ESR1
H3-4
H4C14
MYC
NCOA3
Entrez ID
8290
29028
HPRD ID
04156
10678
Ensembl ID
ENSG00000168148
ENSG00000156802
Uniprot IDs
Q16695
A0A024R9G7
Q6PL18
PDB IDs
2V1D
2YBP
2YBS
3A6N
3T6R
4V2V
4V2W
6OIE
6WAT
6WAU
3DAI
4QSP
4QSQ
4QSR
4QSS
4QST
4QSU
4QSV
4QSW
4QSX
4QUT
4QUU
4TT2
4TT4
4TT6
4TTE
4TU4
4TU6
4TYL
4TZ2
4TZ8
5A5N
5A5O
5A5P
5A5Q
5A5R
5A81
5A82
5A83
5EPB
5F36
5F3A
5LJ0
5QXI
5QXJ
5QXK
5QXL
5QXM
5QXN
5QXO
5QXP
5QXQ
5QXR
5QXS
5QXT
5QXU
5QXV
5QXW
5QXX
5QXY
5QXZ
5QY0
5R4E
5R4F
5R4V
5R4W
5R4X
5R4Y
5R4Z
6CPS
6EPJ
6EPR
6EPS
6EPT
6EPU
6EPV
6EPW
6EPX
6HDN
6HDO
6HI3
6HI4
6HI5
6HI6
6HI7
6HI8
6HIA
6HIB
6HIC
6HID
6HIE
6S55
6S56
6S57
6YB4
Enriched GO Terms of Interacting Partners
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