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LZTR1 and EHMT1
Data Source:
BioGRID
(two hybrid)
LZTR1
EHMT1
Description
leucine zipper like transcription regulator 1
euchromatic histone lysine methyltransferase 1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Endomembrane System
Cul3-RING Ubiquitin Ligase Complex
Recycling Endosome Membrane
Nucleus
Nucleoplasm
Chromosome
Nuclear Body
Molecular Function
Protein Binding
Small GTPase Binding
RNA Polymerase II Transcription Corepressor Binding
P53 Binding
Protein Binding
Methyltransferase Activity
Zinc Ion Binding
Protein-lysine N-methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Histone Methyltransferase Activity (H3-K27 Specific)
C2H2 Zinc Finger Domain Binding
Biological Process
Protein Ubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
DNA Methylation
Chromatin Organization
Histone Methylation
Peptidyl-lysine Monomethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Embryonic Development
Histone H3-K9 Methylation
Response To Fungicide
Negative Regulation Of G0 To G1 Transition
Histone H3-K27 Methylation
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Senescence-Associated Secretory Phenotype (SASP)
PKMTs methylate histone lysines
Regulation of TP53 Activity through Methylation
Transcriptional Regulation by VENTX
Transcriptional Regulation by E2F6
Drugs
Diseases
Kleefstra syndrome; 9q Subtelomeric deletion syndrome
GWAS
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Metabolite levels (
23823483
)
Interacting Genes
55 interacting genes:
AATF
ANKRD53
ASB12
BMPR1B
CEBPZ
CHAF1A
CNOT6L
E2F8
EHMT1
FANK1
GABARAPL2
HCLS1
HDAC4
HRAS
IKBKG
KDM2B
KRAS
L3MBTL3
MCM3
MED16
MED7
MYBL2
NR1H3
NRAS
PAPOLG
PARP1
POLR1B
POLR2B
POLR2E
RAI1
RERE
RIT1
RUVBL1
SCMH1
SND1
SP100
SREBF2
SSX4
STAT1
SUGP2
TAF11
TBX2
TCF19
TFAP2B
TRIM5
TUBGCP4
WWP1
ZBTB1
ZNF137P
ZNF175
ZNF451
ZNF490
ZNF584
ZNF714
ZZZ3
13 interacting genes:
ATXN1
DNMT3A
EED
EZH2
H3-4
H3C1
LIG1
LZTR1
PCBD1
SUMO2
TP53
TRIM15
WIZ
Entrez ID
8216
79813
HPRD ID
08992
07383
Ensembl ID
ENSG00000099949
ENSG00000181090
Uniprot IDs
A0A384NL67
Q8N653
A0A1B0GV09
Q9H9B1
PDB IDs
2IGQ
2RFI
3B7B
3B95
3FPD
3HNA
3MO0
3MO2
3MO5
3SW9
3SWC
4I51
5TTG
5TUZ
5V9J
5VSD
5VSF
6BY9
6MBO
6MBP
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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