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LZTR1 and CNOT6L
Data Source:
BioGRID
(two hybrid)
LZTR1
CNOT6L
Description
leucine zipper like transcription regulator 1
CCR4-NOT transcription complex subunit 6 like
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Endomembrane System
Cul3-RING Ubiquitin Ligase Complex
Recycling Endosome Membrane
Nucleus
Cytoplasm
Cytosol
CCR4-NOT Complex
Molecular Function
Protein Binding
Small GTPase Binding
3'-5'-exoribonuclease Activity
Poly(A)-specific Ribonuclease Activity
Protein Binding
Metal Ion Binding
Biological Process
Protein Ubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Processing
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly
Gene Silencing By RNA
MRNA Destabilization
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Tuberculosis (
24057671
)
Interacting Genes
55 interacting genes:
AATF
ANKRD53
ASB12
BMPR1B
CEBPZ
CHAF1A
CNOT6L
E2F8
EHMT1
FANK1
GABARAPL2
HCLS1
HDAC4
HRAS
IKBKG
KDM2B
KRAS
L3MBTL3
MCM3
MED16
MED7
MYBL2
NR1H3
NRAS
PAPOLG
PARP1
POLR1B
POLR2B
POLR2E
RAI1
RERE
RIT1
RUVBL1
SCMH1
SND1
SP100
SREBF2
SSX4
STAT1
SUGP2
TAF11
TBX2
TCF19
TFAP2B
TRIM5
TUBGCP4
WWP1
ZBTB1
ZNF137P
ZNF175
ZNF451
ZNF490
ZNF584
ZNF714
ZZZ3
2 interacting genes:
LZTR1
ZSCAN1
Entrez ID
8216
246175
HPRD ID
08992
10841
Ensembl ID
ENSG00000099949
ENSG00000138767
Uniprot IDs
A0A384NL67
Q8N653
B4E0K8
H0Y9Z5
Q96LI5
PDB IDs
3NGN
3NGO
3NGQ
5DV2
5DV4
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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