LZTR1 and SND1

Data Source:
BioGRID (two hybrid)

		LZTR1	SND1
Description		leucine zipper like transcription regulator 1	staphylococcal nuclease and tudor domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane	Nucleus Cytoplasm Cytosol Membrane RISC Complex Melanosome Extracellular Exosome Dense Body
	Molecular Function	Protein Binding Small GTPase Binding	Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity Endoribonuclease Activity Protein Binding Cadherin Binding RISC Complex Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction	Osteoblast Differentiation Regulation Of Transcription, DNA-templated RNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Viral Process Gene Silencing By RNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS			Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 32499647 23532257)
Interacting Genes		55 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 GABARAPL2 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RIT1 RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	23 interacting genes: APP CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 PTGER4 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I
Entrez ID		8216	27044
HPRD ID		08992	03714
Ensembl ID		ENSG00000099949	ENSG00000197157
Uniprot IDs		A0A384NL67 Q8N653	A0A140VK49 Q7KZF4
PDB IDs			2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O
Enriched GO Terms of Interacting Partners?
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