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UBE2D3 and SAT1
Data Source:
HPRD
(in vitro)
UBE2D3
SAT1
Description
ubiquitin conjugating enzyme E2 D3
spermidine/spermine N1-acetyltransferase 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Endosome Membrane
Extracellular Exosome
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Diamine N-acetyltransferase Activity
Protein Binding
N-acetyltransferase Activity
Spermidine Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
DNA Repair
Cellular Protein Modification Process
Protein Monoubiquitination
Protein Targeting To Peroxisome
Apoptotic Process
Protein Ubiquitination
BMP Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Cellular Response To Cadmium Ion
Cellular Response To Mercury Ion
Positive Regulation Of Protein Targeting To Mitochondrion
Angiogenesis
Polyamine Biosynthetic Process
Putrescine Catabolic Process
Spermidine Acetylation
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Antigen processing: Ubiquitination & Proteasome degradation
Interconversion of polyamines
Drugs
N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
Keratosis follicularis spinulosa decalvans
GWAS
Asthma and attention deficit hyperactivity disorder (
31619474
)
Diastolic blood pressure (
30224653
)
Interacting Genes
224 interacting genes:
AMBRA1
AMFR
ANAPC11
AREL1
ARIH1
ARIH2
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRCA1
CADPS2
CBL
CBLC
CHFR
CNOT4
CSNK2A1
CUL4B
DBN1
DCUN1D1
DDX58
DTX1
DTX2
DTX3
DTX3L
DVL2
DZIP3
EPS15
ERGIC3
ESR1
F12
FBXL12
FBXL17
FBXL2
FBXO2
FBXO25
FBXO7
FBXW11
FBXW8
FOCAD
FZR1
H2AC4
H3C1
H4C1
HDAC6
HECTD1
HECW1
HECW2
HERC1
HERC2
HUWE1
IKBKG
ITCH
KAT2B
KDM1B
LRSAM1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF7
MARCHF8
MAST1
MDM2
MDM4
MEX3B
MEX3C
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN3
MSL1
MSL2
MUL1
MYCBP2
MYLIP
NBR1
NEDD4
NEDD4L
NFKB1
NFKBIA
NHLRC1
NOSIP
OTUB1
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PCNA
PDCD5
PELI1
PER2
PJA1
PJA2
POLL
POLM
PRPF19
PTEN
RABGEF1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF111
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF14
RNF150
RNF165
RNF166
RNF167
RNF168
RNF181
RNF185
RNF19B
RNF2
RNF216
RNF220
RNF25
RNF26
RNF31
RNF38
RNF4
RNF41
RNF43
RNF5
RNF8
RNFT1
RPLP1
RSPRY1
SAT1
SH3RF1
SHOC2
SIAH1
SIAH2
SMURF1
SMURF2
SOX2
SQSTM1
ST7
STAM2
STAU1
STK25
STUB1
SYVN1
TMEM129
TOPORS
TP53
TP73
TRAF6
TRAIP
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM31
TRIM32
TRIM33
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM58
TRIM62
TRIM63
TRIM68
TRIM69
TRIM7
TRIM72
TRIM8
TUBA1A
UBA1
UBA6
UBASH3B
UBE2O
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR5
UBTD1
UFM1
UHRF1
USP7
UVSSA
WBP2
WSB1
WWP1
WWP2
XIAP
XPNPEP1
ZNRF1
ZNRF2
ZNRF4
98 interacting genes:
ABCB8
ABHD15
APLP1
B4GALT3
BHLHA9
C19orf25
CASP7
CCDC148
CCDC90B
CCHCR1
CDC42EP1
CEP126
CHD3
COPS6
COX6C
CRMP1
CSNK2A1
CSNK2A2
DDX39A
DGKZ
DIPK1B
DMRT3
DNPEP
EEF1G
EIF3D
EPHB6
ERG28
EVA1A
FAM156A
FAM228A
FAM86C1P
FH
FTSJ3
FUNDC2
GAS2L2
GBP2
GDF9
HIF1A
HOXB6
HOXB9
HSPB1
HSPE1
INO80C
ITGA9
JUNB
KAT5
KAT7
KCNA4
KHDC4
LHX3
LNX1
LRIF1
LUC7L2
LYRM7
MED31
MEOX2
MRPL12
MRPL9
MTA1
MYPOP
NIF3L1
NMRK2
NTAQ1
PLGRKT
PRDX2
PSMA1
PTN
RACK1
RBM17
RBM48
REL
RELA
RPLP1
RPP25
SARAF
SAT2
SEPHS1
SETDB1
SNAI2
TACO1
TCF25
TEAD4
TEX43
TLE1
TLE5
TNNI1
TP53
TP53TG1
TSC22D4
TUBB2A
TXN2
UBE2D3
UNC119
USHBP1
UTP14A
VASP
VKORC1
ZHX1
Entrez ID
7323
6303
HPRD ID
04269
02431
Ensembl ID
ENSG00000109332
ENSG00000130066
Uniprot IDs
A0A024RDH2
D6RAH7
P61077
A0A384NQ10
P21673
PDB IDs
1X23
2FUH
3L1Z
3RPG
3UGB
4BVU
4R8P
4S3O
5EGG
5IFR
6CP0
6T7F
2B3U
2B3V
2B4B
2B4D
2B58
2B5G
2F5I
2FXF
2G3T
2JEV
Enriched GO Terms of Interacting Partners
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