Wiki-Pi
About
Search
Browse
People
Updates
Search
UBE2D3 and UHRF1
Data Source:
BioGRID
(pull down, x-ray crystallography)
UBE2D3
UHRF1
Description
ubiquitin conjugating enzyme E2 D3
ubiquitin like with PHD and ring finger domains 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Endosome Membrane
Extracellular Exosome
Chromatin
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
Replication Fork
Nuclear Matrix
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Cis-regulatory Region Sequence-specific DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Methyl-CpG Binding
Nucleosomal Histone Binding
Methylated Histone Binding
Histone Binding
Identical Protein Binding
Hemi-methylated DNA-binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
DNA Repair
Cellular Protein Modification Process
Protein Monoubiquitination
Protein Targeting To Peroxisome
Apoptotic Process
Protein Ubiquitination
BMP Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Cellular Response To Cadmium Ion
Cellular Response To Mercury Ion
Positive Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Transcription By RNA Polymerase II
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Maintenance Of DNA Methylation
Histone Monoubiquitination
Protein Ubiquitination
Histone Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Epithelial Cell Proliferation
Protein Autoubiquitination
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Antigen processing: Ubiquitination & Proteasome degradation
DNA methylation
Drugs
Diseases
GWAS
Asthma and attention deficit hyperactivity disorder (
31619474
)
Diastolic blood pressure (
30224653
)
Birth weight (
31043758
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Mental health study participation (completed survey) (
31263887
)
Systolic blood pressure (
30578418
)
Type 2 diabetes (
30297969
)
Urate levels (
31578528
)
Interacting Genes
224 interacting genes:
AMBRA1
AMFR
ANAPC11
AREL1
ARIH1
ARIH2
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRCA1
CADPS2
CBL
CBLC
CHFR
CNOT4
CSNK2A1
CUL4B
DBN1
DCUN1D1
DDX58
DTX1
DTX2
DTX3
DTX3L
DVL2
DZIP3
EPS15
ERGIC3
ESR1
F12
FBXL12
FBXL17
FBXL2
FBXO2
FBXO25
FBXO7
FBXW11
FBXW8
FOCAD
FZR1
H2AC4
H3C1
H4C1
HDAC6
HECTD1
HECW1
HECW2
HERC1
HERC2
HUWE1
IKBKG
ITCH
KAT2B
KDM1B
LRSAM1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF7
MARCHF8
MAST1
MDM2
MDM4
MEX3B
MEX3C
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN3
MSL1
MSL2
MUL1
MYCBP2
MYLIP
NBR1
NEDD4
NEDD4L
NFKB1
NFKBIA
NHLRC1
NOSIP
OTUB1
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PCNA
PDCD5
PELI1
PER2
PJA1
PJA2
POLL
POLM
PRPF19
PTEN
RABGEF1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF111
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF14
RNF150
RNF165
RNF166
RNF167
RNF168
RNF181
RNF185
RNF19B
RNF2
RNF216
RNF220
RNF25
RNF26
RNF31
RNF38
RNF4
RNF41
RNF43
RNF5
RNF8
RNFT1
RPLP1
RSPRY1
SAT1
SH3RF1
SHOC2
SIAH1
SIAH2
SMURF1
SMURF2
SOX2
SQSTM1
ST7
STAM2
STAU1
STK25
STUB1
SYVN1
TMEM129
TOPORS
TP53
TP73
TRAF6
TRAIP
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM31
TRIM32
TRIM33
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM58
TRIM62
TRIM63
TRIM68
TRIM69
TRIM7
TRIM72
TRIM8
TUBA1A
UBA1
UBA6
UBASH3B
UBE2O
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR5
UBTD1
UFM1
UHRF1
USP7
UVSSA
WBP2
WSB1
WWP1
WWP2
XIAP
XPNPEP1
ZNRF1
ZNRF2
ZNRF4
26 interacting genes:
DNMT1
DNMT3A
ERCC1
ERG
FANCD2
H2AC4
H2BC3
H3-4
H3C1
H3C13
H3C14
H3C15
H4C14
KAT5
LASP1
LIG1
MBD4
MUS81
PCLAF
PCNA
PRKACA
TP53
UBE2D1
UBE2D3
UBE2N
UHRF2
Entrez ID
7323
29128
HPRD ID
04269
06992
Ensembl ID
ENSG00000109332
ENSG00000276043
Uniprot IDs
A0A024RDH2
D6RAH7
P61077
A0A087WVR3
Q96T88
PDB IDs
1X23
2FUH
3L1Z
3RPG
3UGB
4BVU
4R8P
4S3O
5EGG
5IFR
6CP0
6T7F
2FAZ
2L3R
2LGG
2LGK
2LGL
2PB7
3ASK
3ASL
3BI7
3CLZ
3DB3
3DB4
3DWH
3FL2
3SHB
3SOU
3SOW
3SOX
3T6R
3ZVY
3ZVZ
4GY5
4QQD
5C6D
5IAY
5XPI
5YY9
5YYA
6B9M
6IIW
6VCS
6VED
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?