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TSG101 and INCA1
Data Source:
BioGRID
(two hybrid)
TSG101
INCA1
Description
tumor susceptibility 101
inhibitor of CDK, cyclin A1 interacting protein 1
Image
No pdb structure
GO Annotations
Cellular Component
ESCRT I Complex
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Microtubule Organizing Center
Cytosol
Plasma Membrane
Endosome Membrane
Early Endosome Membrane
Late Endosome Membrane
Host Cell
Extracellular Exosome
Flemming Body
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Coactivator Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Cyclin Binding
Identical Protein Binding
Protein-containing Complex Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Protein Monoubiquitination
Extracellular Transport
Cell Cycle Arrest
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Viral Budding
Cell Division
Intracellular Transport Of Virus
Autophagosome Maturation
Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Drugs
Diseases
GWAS
Intraocular pressure (
29235454
)
Obesity-related traits (
23251661
)
Interacting Genes
120 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
ARRDC1
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GMCL1
GOLM1
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
PDCD6IP
PDLIM7
PIAS1
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SNAPIN
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNIP1
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
ZWINT
236 interacting genes:
ABI2
ACY3
AKAP8L
ANKRD28
ARMC7
ASPSCR1
ATG5
ATP6V0D2
ATPAF2
BAG3
BANF2
BOLA3
BPIFA1
C10orf55
C19orf54
C1orf35
C1orf50
C1orf56
C22orf39
CABP5
CCBE1
CCDC57
CCDC78
CCNA1
CDA
CDC23
CDK18
CDK2
CDK4
CDKN1A
CDKN2B
CDKN2D
CEP72
CHCHD2
CHCHD5
CHRD
CINP
CKS1B
CLIC3
CLK3
COL8A1
CPSF1
CSDC2
CSTF2
CTNNBIP1
CTTNBP2
CYSRT1
DAZAP2
DEF6
DMRT3
DMRTB1
DOK4
DPH7
DUSP13
EFEMP2
EMD
EPHB6
EXOSC8
FAAP20
FAIM
FEM1A
FGF16
FHL2
FMR1
FRS3
GEM
GEMIN2
GRB2
GRXCR1
GSTO2
GTF2H5
GTPBP3
GYS1
HAUS1
HCK
HDAC4
HEMK1
HENMT1
HNRNPF
HOMER3
HOXA1
HR
HSD17B14
HYI
IL36RN
ILF2
KCTD7
KCTD9
KIAA1217
KIR2DL4
KLHL26
KLHL42
KRT33B
KRT5
KRT75
KRTAP15-1
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP5-6
KRTAP6-2
KRTAP6-3
KRTAP9-3
LENG8
LGALS3
LHX3
LMNTD2
LMO2
LMO3
LSM3
LYPLA2
MAD2L2
MAGED4B
MAGOHB
MALSU1
MARF1
MARK1
MATN3
MBLAC1
METAP1
MPP1
MSRB1
MTMR9
NATD1
NCK2
NDUFAF3
NEDD9
NEIL2
NEK6
NFKBID
NHSL2
NME7
NMRK1
NPAS2
NTAQ1
NUBP2
NUDT16L1
NUDT22
OR6B1
OSGIN1
PADI3
PATE1
PCSK5
PCYT2
PDP1
PEF1
PFDN5
PHF1
PLA2G10
PLSCR3
POLR1C
POLR3C
POP5
POU4F2
PPP1R32
PRPH
PSMB2
PSMB8
PTGER3
R3HDM2
RAB5C
RALB
RAMAC
RBPMS
RECK
RFC3
RIPPLY3
RNF26
SAP18
SCNM1
SEC14L4
SHFL
SLC22A18AS
SMG9
SMUG1
SNRPB
SPAG8
SPG21
SPOUT1
SPRY1
STAMBPL1
STK16
STT3B
SUOX
TBC1D7
TCL1A
TEAD4
TEKT4
TEX12
TFAP2A
TFAP2D
TFAP4
TFG
THAP6
THRSP
TIAL1
TPRX1
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIB3
TRIM26
TRIM55
TRIM63
TRIM68
TRIP13
TRIP6
TSEN15
TSG101
TSSK3
TSTD2
TXNDC17
UBASH3B
UBE2D4
UBE2Z
UBTD2
UBXN2B
UFM1
UFSP1
VEZF1
VGLL3
VPS26C
VPS28
WWOX
YIPF3
YOD1
ZDHHC24
ZFAND3
ZMYND12
ZMYND19
ZNF205-AS1
ZNF32
ZNF446
ZNF747
ZNF765
ZNRD2
Entrez ID
7251
388324
HPRD ID
03229
17150
Ensembl ID
ENSG00000074319
ENSG00000196388
Uniprot IDs
Q99816
Q0VD86
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6VME
Enriched GO Terms of Interacting Partners
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