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TSG101 and HAUS1
Data Source:
BioGRID
(two hybrid, two hybrid)
TSG101
HAUS1
Description
tumor susceptibility 101
HAUS augmin like complex subunit 1
Image
No pdb structure
GO Annotations
Cellular Component
ESCRT I Complex
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Microtubule Organizing Center
Cytosol
Plasma Membrane
Endosome Membrane
Early Endosome Membrane
Late Endosome Membrane
Host Cell
Extracellular Exosome
Flemming Body
Spindle Pole
Centrosome
Cytosol
HAUS Complex
Mitotic Spindle Microtubule
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Coactivator Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Molecular_function
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Protein Monoubiquitination
Extracellular Transport
Cell Cycle Arrest
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Viral Budding
Cell Division
Intracellular Transport Of Virus
Autophagosome Maturation
Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
G2/M Transition Of Mitotic Cell Cycle
Centrosome Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Pathways
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes
120 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
ARRDC1
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GMCL1
GOLM1
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
PDCD6IP
PDLIM7
PIAS1
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SNAPIN
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNIP1
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
ZWINT
82 interacting genes:
AK8
ARFIP2
ATP6V1D
BFSP2
BLOC1S6
BORCS6
C3orf62
CAGE1
CBY2
CCDC136
CCDC57
CCHCR1
CDR2
CENPP
CEP170P1
CEP44
CEP55
CEP57L1
CEP63
CEP70
DCTN2
DMD
DTNBP1
FAM161B
FGFR1OP2
GOLGA2
HGS
HOOK2
IFIT3
IFT20
INCA1
KDM1A
KIFC3
KRT1
KRT15
KRT18
KRT19
KRT3
KRT31
KRT38
KRT40
KXD1
LDOC1
LURAP1
MAD1L1
MAGEA6
MCM10
MCM3
MED4
MED7
MIPOL1
MTUS2
NDC80
NECAB2
NINL
NUP54
NUP62
ODAD1
PDE4DIP
PIBF1
PKN1
POLR3C
SPAG5
SSC5D
STX11
SYCE1
SYCE3
TEAD4
TFIP11
TFPT
TRAF1
TRIM23
TRIM27
TRIM54
TRIM69
TSG101
TXN2
USHBP1
VPS37C
VPS52
WASHC3
ZNF471
Entrez ID
7251
115106
HPRD ID
03229
16385
Ensembl ID
ENSG00000074319
ENSG00000152240
Uniprot IDs
Q99816
Q96CS2
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6VME
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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