VAMP7 and SNAP23

Data Source:
HPRD (in vitro)

		VAMP7	SNAP23
Description		vesicle associated membrane protein 7	synaptosome associated protein 23
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GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Trans-Golgi Network Plasma Membrane Membrane Lamellipodium Secretory Granule Filopodium Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Triglyceride Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Transport Along Microtubule Vesicle Fusion With Golgi Apparatus Membrane Organization Autophagosome Maturation Positive Regulation Of Histamine Secretion By Mast Cell	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion
Pathways		trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Interleukin-12 signaling	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		11 interacting genes: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		6845	8773
HPRD ID		02084	03962
Ensembl ID		ENSG00000124333	ENSG00000092531
Uniprot IDs		A0A024R061 A0A024R074 P51809	A0A024R9R8 A8K287 O00161
PDB IDs		2DMW	1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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