SNAP23 and STXBP2

Data Source:
HPRD (in vivo, in vitro)

		SNAP23	STXBP2
Description		synaptosome associated protein 23	syntaxin binding protein 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse	Extracellular Region Cytosol Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Cytolytic Granule Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion	Leukocyte Mediated Cytotoxicity Platelet Degranulation Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation
Pathways		ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation	Platelet degranulation Other interleukin signaling
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P	13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		8773	6813
HPRD ID		03962	03423
Ensembl ID		ENSG00000092531	ENSG00000076944
Uniprot IDs		A0A024R9R8 A8K287 O00161	Q15833 Q53GF4
PDB IDs		1NHL 3ZUS	4CCA
Enriched GO Terms of Interacting Partners?
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