VAMP7 and AGFG1

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		VAMP7	AGFG1
Description		vesicle associated membrane protein 7	ArfGAP with FG repeats 1
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GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Trans-Golgi Network Plasma Membrane Membrane Lamellipodium Secretory Granule Filopodium Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse	Nuclear Pore Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Triglyceride Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Transport Along Microtubule Vesicle Fusion With Golgi Apparatus Membrane Organization Autophagosome Maturation Positive Regulation Of Histamine Secretion By Mast Cell	MRNA Export From Nucleus Multicellular Organism Development Spermatogenesis Cell Differentiation Positive Regulation Of GTPase Activity Membrane Organization
Pathways		trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Interleukin-12 signaling	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Airway hyperresponsiveness ( 23984888) Asthma ( 31959851) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		11 interacting genes: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7	14 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 PKIA POLE2 RNF216 TRIM54 VAMP7 XPO1
Entrez ID		6845	3267
HPRD ID		02084	02918
Ensembl ID		ENSG00000124333	ENSG00000173744
Uniprot IDs		A0A024R061 A0A024R074 P51809	A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594
PDB IDs		2DMW	2D9L 2OLM 2VX8
Enriched GO Terms of Interacting Partners?
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