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ELOVL4 and BIK
Data Source:
BioGRID
(two hybrid)
ELOVL4
BIK
Description
ELOVL fatty acid elongase 4
BCL2 interacting killer
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Endomembrane System
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
Protein Binding
Biological Process
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Apoptotic Process
Male Gonad Development
Apoptotic Mitochondrial Changes
Positive Regulation Of Protein-containing Complex Assembly
Regulation Of Apoptotic Process
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Prostate cancer (
25939597
21743057
)
Prostate cancer (SNP x SNP interaction) (
22219177
)
Interacting Genes
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
95 interacting genes:
ADGRE2
ADIPOQ
AIG1
ALG8
ANKRD46
APOD
APP
ASB11
BCL2
BCL2A1
BCL2L1
BCL2L10
BCL2L2
BMP10
BNIP3
BRICD5
BTN2A2
C14orf180
C3orf52
C4orf3
CD53
CD72
CLDN19
CMTM5
CMTM7
CNIH1
CNIH3
CREB3
CRKL
CTXN3
CXCL16
CYB561
CYB5B
ELOVL4
ERGIC3
EXOC3L2
FAM209A
FAM241B
FAM3C
FATE1
FCGR1A
GPX8
GRM2
INSIG2
KCNN4
MARCHF5
MCL1
MS4A13
NAT8
NR2F2
NRM
PBX3
PGAP2
PGRMC1
PLN
PLP1
PLP2
PLPP4
REEP4
RUSF1
S100A1
SCAMP4
SEC22A
SELENOK
SERP1
SERP2
SLC35E3
SLC37A4
SLC39A7
SMIM1
SOCS3
STRIT1
STX8
TANK
TMBIM1
TMEM107
TMEM11
TMEM14B
TMEM14C
TMEM199
TMEM222
TMEM229B
TMEM243
TMEM254
TMEM60
TMEM80
TMEM86B
TMEM97
TRARG1
TSPO2
UBE2D1
UBIAD1
VAMP3
VAMP5
ZFPL1
Entrez ID
6785
638
HPRD ID
05697
04547
Ensembl ID
ENSG00000118402
ENSG00000100290
Uniprot IDs
Q9GZR5
A0A024R4X6
Q13323
PDB IDs
2IPE
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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