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ELOVL4 and PLN
Data Source:
BioGRID
(two hybrid)
ELOVL4
PLN
Description
ELOVL fatty acid elongase 4
phospholamban
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Mitochondrion
Endoplasmic Reticulum
Membrane
Mitochondrial Membrane
Vesicle
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Calcium Ion-transporting ATPase Complex
Molecular Function
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
Enzyme Inhibitor Activity
Protein Binding
ATPase Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
ATPase Binding
Biological Process
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Regulation Of The Force Of Heart Contraction
Calcium Ion Transport
Notch Signaling Pathway
Blood Circulation
Regulation Of Heart Contraction
Response To Zinc Ion
Negative Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of ATPase Activity
Response To Insulin
Response To Testosterone
Negative Regulation Of Catalytic Activity
Cardiac Muscle Tissue Development
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Calcium Ion Transport
Negative Regulation Of Calcium Ion Transport
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Binding
Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Ion homeostasis
Ion transport by P-type ATPases
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Atrial fibrillation (
28416818
30061737
)
Cardiac structure and function (
19584346
)
QRS complex (Sokolow-Lyon) (
27659466
)
QRS duration (
27577874
27659466
)
QT interval (
23166209
24952745
19305408
19305409
19587794
29874175
)
Resting heart rate (
27798624
)
Interacting Genes
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
64 interacting genes:
ARL13B
ASGR2
ATP2A1
ATP2A2
ATP6V0E1
BCL2L13
BIK
CD53
CLDN7
CLEC2D
CPLX4
CREB3
CREB3L1
DMPK
DVL3
EDA
ELOVL4
FAM209A
FKBP8
FNDC9
GJA8
GPR152
GPR37L1
GPX8
HIBADH
HSD17B13
KIR2DL3
LDLRAD1
LSMEM2
MFF
MFSD5
MGST2
MGST3
MS4A7
MTIF3
MUC1
PLPPR1
PPP1R3A
PRKACA
RTN3
S100A1
SAR1A
SDC3
SIT1
SLC14A2
SLC30A8
SLC34A2
SLC35C2
SLC39A2
SLN
SPACA1
SPAG4
STX1A
STX2
TMEM106C
TMEM179B
TMEM205
TMEM31
TMEM45A
TMEM45B
TMEM52B
TMEM79
TMEM86B
TMPRSS2
Entrez ID
6785
5350
HPRD ID
05697
01395
Ensembl ID
ENSG00000118402
ENSG00000198523
Uniprot IDs
Q9GZR5
P26678
Q5R352
PDB IDs
1K9N
1KCH
1PLN
1PLP
1PSL
1ZLL
2HYN
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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