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SNX1 and SYP
Data Source:
BioGRID
(two hybrid)
SNX1
SYP
Description
sorting nexin 1
synaptophysin
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Endosome
Golgi Apparatus
Cytosol
Endosome Membrane
Membrane
Lamellipodium
Retromer Complex
Retromer, Tubulation Complex
Early Endosome Membrane
Vesicle
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Synaptic Vesicle
Integral Component Of Synaptic Vesicle Membrane
Synaptic Vesicle Membrane
Neuromuscular Junction
Presynaptic Membrane
Neuron Projection
Terminal Bouton
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone
Excitatory Synapse
Schaffer Collateral - CA1 Synapse
Molecular Function
Epidermal Growth Factor Receptor Binding
Insulin Receptor Binding
Protein Binding
Phosphatidylinositol Binding
Identical Protein Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Transferrin Receptor Binding
Leptin Receptor Binding
Protein Binding
Cholesterol Binding
Syntaxin-1 Binding
SH2 Domain Binding
Identical Protein Binding
Protein Self-association
Biological Process
Intracellular Protein Transport
Receptor Internalization
Early Endosome To Golgi Transport
Retrograde Transport, Endosome To Golgi
Positive Regulation Of Protein Catabolic Process
Lamellipodium Morphogenesis
Endocytosis
Synaptic Vesicle Maturation
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Short-term Neuronal Synaptic Plasticity
Synaptic Vesicle Endocytosis
Synaptic Vesicle Membrane Organization
Cellular Response To Organic Substance
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Opioid Receptor Signaling Pathway
Pathways
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Interacting Genes
48 interacting genes:
ACVR1B
ACVR2B
AGTRAP
APP
ARFIP2
ARL6IP1
ARMC12
ATXN7
CCDC148
CHRNG
CMTM4
CMTM5
COQ3
EGFR
F2R
FAM25A
FAM25C
FAM25G
FKBP7
FUNDC1
HCCS
HGS
INSR
LEPR
LIME1
MPC2
PDGFRB
PLIN3
RABAC1
REEP5
REEP6
RHEX
RTN3
RTN4
SASH1
SDCBP
SDR16C5
SFT2D1
SH3GLB1
SNX2
SNX32
SNX6
SYNGR1
SYP
TK1
TMEM239
UFD1
VPS35
41 interacting genes:
AP1G1
ARFIP2
CAND2
CD160
DIABLO
FARS2
GAB1
GDNF
GRB2
HSFX1
HSFX2
JOSD2
LNPK
MIEF1
MIEF2
MRM1
MRRF
MTERF3
MYG1
NDRG4
PBX3
PITPNC1
PLIN3
PNKP
PPIF
PTCD1
PTPN9
RBFA
SH3GLB1
SIAH1
SIAH2
SMG9
SNX1
SPG21
SSX5
STARD4
THAP4
TUFM
VAMP2
WDFY2
WIPI2
Entrez ID
6642
6855
HPRD ID
03171
02435
Ensembl ID
ENSG00000028528
ENSG00000102003
Uniprot IDs
Q13596
P08247
PDB IDs
2I4K
4FZS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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