SNX1 and RTN3

Data Source:
BioGRID (two hybrid)

		SNX1	RTN3
Description		sorting nexin 1	reticulon 3
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Apoptotic Process Viral Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation
Pathways			Synaptic adhesion-like molecules
Drugs
Diseases
GWAS
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	30 interacting genes: AGTR1 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391
Entrez ID		6642	10313
HPRD ID		03171	18516
Ensembl ID		ENSG00000028528	ENSG00000133318
Uniprot IDs		Q13596	A0A024R5C4 O95197
PDB IDs		2I4K 4FZS	7BRU
Enriched GO Terms of Interacting Partners?
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