SNX1 and TMEM239

Data Source:
BioGRID (two hybrid)

		SNX1	TMEM239
Description		sorting nexin 1	transmembrane protein 239
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Integral Component Of Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	67 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MFSD14B MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35C2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5
Entrez ID		6642	100288797
HPRD ID		03171
Ensembl ID		ENSG00000028528	ENSG00000198326
Uniprot IDs		Q13596	Q8WW34
PDB IDs		2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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