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SKIL and KRT81
Data Source:
HPRD
(two hybrid)
SKIL
KRT81
Description
SKI like proto-oncogene
keratin 81
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Transcription Regulator Complex
Protein-containing Complex
Extracellular Space
Cytosol
Keratin Filament
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
SMAD Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Blastocyst Formation
Lymphocyte Homeostasis
Cell Cycle Arrest
Transforming Growth Factor Beta Receptor Signaling Pathway
Spermatogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Response To Cytokine
Negative Regulation Of Cell Differentiation
Positive Regulation Of Axonogenesis
Lens Fiber Cell Differentiation
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Keratinization
Cornification
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Keratinization
Formation of the cornified envelope
Drugs
Diseases
Monilethrix
GWAS
Estimated glomerular filtration rate (
31152163
)
Glomerular filtration rate (creatinine) (
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Prostate cancer (
21743467
)
Diisocyanate-induced asthma (
25918132
)
Interacting Genes
96 interacting genes:
ASCC3
CAMSAP1
CBX4
CDC16
CDC27
CHD3
CHPF
COL4A2
CPNE1
CPNE2
CPNE4
CXXC5
DEUP1
DHX30
DRG1
EEF1G
EIF4G2
ESR1
FAF1
FBLN1
FN1
FZR1
GAS8
GLUL
GOLGB1
HEY1
HEYL
HIPK1
HIPK3
HNRNPLL
IL36RN
KRT81
LRP1
MACF1
MORC4
MVP
MYG1
NCOR1
NCOR2
NEFL
NID1
NID2
NXF3
OIP5
PAPPA
PIAS1
PIAS3
PIAS4
PLCD3
PPL
PSG3
PSMC2
PTPRF
PYCR2
RNF4
RPS27
SASH1
SETDB1
SKI
SMAD1
SMAD2
SMAD3
SMAD4
SMUG1
SMURF2
SNRNP70
SNX17
SPARCL1
SRP72
STK16
SVEP1
TDG
TDP2
TFPI2
THAP5
THSD7A
TLE5
TPM2
TRAK1
TRIM62
TRIM69
TSKU
TTF2
UBE2I
UIMC1
USP25
VPS28
XPA
XRCC6
ZBTB3
ZBTB6
ZMYM2
ZMYM5
ZNF106
ZNF200
ZZEF1
23 interacting genes:
CYSRT1
HOXA1
KRT14
KRT15
KRT16
KRT18
KRT19
KRT26
KRT27
KRT28
KRT31
KRT34
KRT35
KRT37
KRT38
KRT39
KRT40
KXD1
LCA5L
MEOX2
OIP5
OTX1
SKIL
Entrez ID
6498
3887
HPRD ID
01319
03691
Ensembl ID
ENSG00000136603
ENSG00000205426
Uniprot IDs
P12757
Q14533
PDB IDs
3EQ5
5C4V
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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