KRT81 and KRT14

Data Source:
BioGRID (two hybrid)

		KRT81	KRT14
Description		keratin 81	keratin 14
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Keratin Filament	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Basal Part Of Cell Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Keratin Filament Binding
	Biological Process	Keratinization Cornification	Aging Epidermis Development Response To Zinc Ion Response To Ionizing Radiation Keratinization Hemidesmosome Assembly Hair Cycle Intermediate Filament Bundle Assembly Cornification
Pathways		Keratinization Formation of the cornified envelope	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases		Monilethrix	Naegeli-Franceschetti-Jadassohn syndrome Dermatopathia pigmentosa reticularis Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Diisocyanate-induced asthma ( 25918132)
Interacting Genes		23 interacting genes: CYSRT1 HOXA1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT37 KRT38 KRT39 KRT40 KXD1 LCA5L MEOX2 OIP5 OTX1 SKIL	32 interacting genes: ABI2 ABI3 AMOT APC BFSP2 CTTNBP2 DST ENKD1 GAS8 HGS HSPA5 KIFC3 KRT1 KRT3 KRT5 KRT6C KRT72 KRT78 KRT79 KRT80 KRT81 KRT86 OIP5 PKP1 PRPH PUS10 SDCBP SMARCE1 TCHP TRADD UBASH3A USHBP1
Entrez ID		3887	3861
HPRD ID		03691	01017
Ensembl ID		ENSG00000205426	ENSG00000186847
Uniprot IDs		Q14533	P02533
PDB IDs			3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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