VPS16 and HOOK1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS16	HOOK1
Description		VPS16 core subunit of CORVET and HOPS complexes	hook microtubule tethering protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly
Pathways
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417	30 interacting genes: AKTIP ANK3 ANKRD23 CDC5L CDK4 CWF19L2 FAM161A FHIP1B HOOK2 HOOK3 LMO2 MEOX2 PIAS2 SYCE1 TBC1D7 TFIP11 USP2 UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80
Entrez ID		64601	51361
HPRD ID		12259	07428
Ensembl ID		ENSG00000215305	ENSG00000134709
Uniprot IDs		Q9H269	Q9UJC3
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?
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