VPS16 and VPS33A

Data Source:
HPRD (in vivo)

		VPS16	VPS33A
Description		VPS16 core subunit of CORVET and HOPS complexes	VPS33A core subunit of CORVET and HOPS complexes
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Lysosome Lysosomal Membrane Early Endosome Late Endosome Autophagosome AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Clathrin Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Vacuole Fusion, Non-autophagic Autophagosome Maturation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome To Lysosome Transport Vesicle-mediated Transport Platelet Formation Melanosome Localization Lysosome Localization Regulation Of Lysosomal Lumen PH Regulation Of Developmental Pigmentation Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		17 interacting genes: AKTIP EXOC8 FBXO7 GNG13 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A ZNF417	7 interacting genes: MON1A MON1B ROPN1 TNKS VPS11 VPS16 VPS18
Entrez ID		64601	65082
HPRD ID		12259	15651
Ensembl ID		ENSG00000215305	ENSG00000139719
Uniprot IDs		Q9H269	Q96AX1
PDB IDs		4BX9	4BX8 4BX9
Enriched GO Terms of Interacting Partners?
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