HOOK1 and VPS39

Data Source:
HPRD (in vivo)

		HOOK1	VPS39
Description		hook microtubule tethering protein 1	VPS39 subunit of HOPS complex
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex	Cytoplasm Lysosomal Membrane Membrane AP-3 Adaptor Complex HOPS Complex Late Endosome Membrane
	Molecular Function	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding	Protein Binding
	Biological Process	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly	Intracellular Protein Transport Autophagy Endosome To Lysosome Transport Endosomal Vesicle Fusion Late Endosome To Lysosome Transport Retrograde Transport, Endosome To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		30 interacting genes: AKTIP ANK3 ANKRD23 CDC5L CDK4 CWF19L2 FAM161A FHIP1B HOOK2 HOOK3 LMO2 MEOX2 PIAS2 SYCE1 TBC1D7 TFIP11 USP2 UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80	7 interacting genes: HOOK1 RAB7A RILP SNW1 STAT3 TFIP11 VPS11
Entrez ID		51361	23339
HPRD ID		07428	10300
Ensembl ID		ENSG00000134709	ENSG00000166887
Uniprot IDs		Q9UJC3	A0A024R9L9 Q96JC1
PDB IDs			6ZE9
Enriched GO Terms of Interacting Partners?
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