ARAP3 and PARD6B

Data Source:
BioGRID (two hybrid)

		ARAP3	PARD6B
Description		ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	par-6 family cell polarity regulator beta
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Cytoskeleton Plasma Membrane Lamellipodium	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding	Protein Kinase C Binding Protein Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways		Rho GTPase cycle	Tight junction interactions
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Diffuse large B cell lymphoma ( 25261932) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Household income ( 31844048) Lung cancer ( 28604730) Mean arterial pressure ( 27618448) Offspring birth weight ( 31043758)	Bipolar disorder ( 21771265)
Interacting Genes		10 interacting genes: ANKS1A ARHGEF6 CD2AP CLNK GGA3 INPPL1 PARD6B SAMHD1 SH3KBP1 TNKS2	33 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4
Entrez ID		64411	84612
HPRD ID		09441	18703
Ensembl ID		ENSG00000120318	ENSG00000124171
Uniprot IDs		Q05CH1 Q8WWN8 Q9H7C1	Q9BYG5
PDB IDs		2KG5 2LNW 5JCP 5JD0 7A9B
Enriched GO Terms of Interacting Partners?
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