PARD6B and PARD3B

Data Source:
HPRD (in vitro)

		PARD6B	PARD3B
Description		par-6 family cell polarity regulator beta	par-3 family cell polarity regulator beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Adherens Junction Bicellular Tight Junction Cell Cortex Endomembrane System Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Junction Complex
	Molecular Function	Protein Kinase C Binding Protein Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly	Microtubule Cytoskeleton Organization Cell Cycle Cell Adhesion Protein Localization Establishment Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Establishment Of Centrosome Localization
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Adult body size ( 32376654) AIDS progression ( 21502085) Aluminium levels ( 26025379) Attention deficit hyperactivity disorder ( 30563984) Autism ( 22843504) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hippocampal volume ( 25625606) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Knee osteoarthritis ( 18471798) Nicotine dependence symptom count ( 25555482) Post bronchodilator FEV1/FVC ratio ( 26634245) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		33 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	9 interacting genes: CASK GAA INSC MARK2 PARD6B RBM5 RPS6KA1 YWHAE YWHAG
Entrez ID		84612	117583
HPRD ID		18703	09795
Ensembl ID		ENSG00000124171	ENSG00000116117
Uniprot IDs		Q9BYG5	Q8TEW8
PDB IDs
Enriched GO Terms of Interacting Partners?
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